Miaka Yūki, an average middle school student caught up in studying for exams, is sucked into an ancient Chinese novel titled "The Universe of Four Gods". There she discovers that she is in an ancient country in what is now China, Konan, and is to be the Priestess of one of the four gods, Suzaku. As the priestess, her duty is to gather the Seven Seishi of Suzaku, who are to be her protectors. Once they are gathered, the priestess will summon the god Suzaku and bring peace between the warring lands, Konan and Kutou. But it's harder than it seems. Along the road, many hardships are faced, as Miaka's best friend Yui Hongo enters the book and becomes her rival, the priestess of Seiryuu in the land of Kutou. Who summons their god first is up to the courage and skill of the priestesses and their seishi, as they meet triumphs and tragedies along the way.

[Source: Anime News Network]

A year after the events of Fushigi Yuugi, Tamahome is pulled back into the book and is sent on a complicated ride through illusion, confusion, and betrayal. Meanwhile, Yui is acting oddly and Miaka is heartbroken over the loss of Tamahome, while Keisuke and Tetsuya try to discover what is going on with the book.

[Source: Anime News Network]

Miaka and Taka (Tamahome's reborn out-of-the-book self) return to the Universe of the Four Gods to try and restore Tamahome's memories to Taka. This is not as easy as it sounds, however, when the evil Tenkou shows up to rain on their parade. He manages to thwart most of their attempts at getting Taka's memories back, and uses his newfound power to summon the Gods outside the book.

[Source: Anime News Network]

Taka (technically Tamahome) and Miaka are now happily married and only six months before their new family would be born, but an obessed girl named Mayo would do anything to make Taka hers. She enters the world of the Four Gods, determined to win Taka's heart and be the new priestess.